header



 

Scientific Program

Tuesday Oct 6, 2009

 

 

 

 

16.00-19.00

Registration

 

19.00-22.00

Get Together Party

 

 

 

Wednesday, Oct 7, 2009

 

 

 

 

8.00-9.00

Registration

 

 

 

 

Chairman: K. Vékey

 

 

 

 

9.00-9.20

Opening

WePl01

9.20-10.00

H. E. Meyer, C. Mölleken, B. Sitek, C. Henkel, G. Poschmann, B. Sipos, S. Wiese, B. Warscheid, C. Broelsch, M. Reiser, S. L. Friedman, I. Tornøe, A. Schlosser, G. Klöppel, W. Schmiegel, U. Holmskov, K. Stühler

 

 

High Performance Proteomics - a successful way to Biomarkers

WeOr01

10.00-10.20

S. R. Pennington

 

 

Integrating biomedical proteomic biomarker discovery with quantification and validation

 

 

 

 

10.20-11.00

Coffee-break

 

 

 

Chairman: R. Zubarev

 

 

 

WePl02

11.00-11.40

H. Mischak

 

 

Proteome Analysis Using Capillary Electrophoresis Coupled Mass Spectrometry: Basic Principles and Clinical Diagnostic Applications

WeOr02

11.40-12.00

S. Surinova, M. Dziechciarková, M. Skrovina, M. Hajdúch, R. Aebersold

 

 

Detection of potential colorectal cancer markers in patients’ plasma

WeOr03

12.00-12.20

C. Lenz, D. Merkel, V. Kruft

 

 

New workflows for the quantitation of protein biomarkers using hybrid triple quadrupole/linear ion trap mass spectrometry

 

 

 

 

12.20-14.00

Lunch

 

 

 

Chairman: M. Karas

 

 

 

WePl03

14.00-14.40

R. A. Zubarev, C. Marin Vicente

 

 

Pathway Search Engine - New Development

WeOr04

14.40-15.00

A. Malinowska, A. Szybinska, T. Rubel, M. Kistowski, F. Van Leuven, M. Dadlez

 

 

A proteomic approach to analysis of synaptosomes from mouse models of Alzheimer's disease

WeOr05

15.00-15.20

M. A. McDowall, K. Giles, J. Hoyes, J. Langridge, T. McKenna

 

 

An Integrated LC/MS Strategy for High Definition Biomarker Discovery and Verification

 

 

 

 

15.20-17.00

Poster session 1 and coffee break

 

 

 

 

16.00-17.00

Workshop discussing the interaction between genetics and proteomics (coordinated by R. Zubarev)

 

 

 

Chairman: H. Mischak

 

 

 

WePl04

17.00-17.40

J. Amster

 

 

Methodology Developments for High Throughput Analysis of Prokaryotic Proteomes

WeOr06

17.40-18.00

I. Selicharova, M. Sanda, E. Matouskova, P. Kleiblova, Z. Kleibl

 

 

Changes in proteomes of normal mammary epithelial cells possibly related to breast cancer predisposition in BRCA1 mutation carriers

 

 

 

 

18.30-20.00

Waters Celebration Seminar

 

 

Dr Mark A. McDowall

Strategic Development Manager MS, Waters MS Technologies Research Centre, Manchester, UK.

 

 

Waters SYNAPT G2 ...a New Dimension High Definition Mass Spectrometry.

 

 

Dr Therese McKenna

Technical Manager Proteomics, Waters MS Technologies Research Centre, Manchester, UK.

 

 

An Introduction to High Definition Proteomics

 

Complimentary refreshments will be offered to registered participants

 

 

 

Thursday, Oct 8, 2009

 

 

 

Chairman: G. Allmaier

 

 

 

ThPl01

9.00-9.40

H. Skalnikova, P. Vodicka, P. Halada, M. Marsala, J. Motlik, S. J. Gadher, H. Kovarova

 

 

Targeted Neural Stem Cell Differentiation and related cell based therapy in spinal cord injury

ThOr01

9.40-10.00

T. Janáky, J. Kovacs, J. Szeline Szomor, D. Simon, I. Foldi, R. Berkecz, Z. Szabo

 

 

Quantification of proteins in proteomics

ThOr02

10.00-10.20

G. Mitulović, A. J. Alpert, V. Paulitschke, R. W. Schmid, S. Schmid, C. Gerner

 

 

Enrichment and Separation of Proteins of Human Melanoma via Mixed Mode Ion Exchange Chromatography

 

 

 

 

10.20-11.00

Coffee-break

 

 

 

Chairman: H.E. Meyer

 

 

 

ThPl02

11.00-11.40

W. J. Griffiths, Y. Wang

 

 

Liver and Brain Proteomics

ThOr03

11.40-12.00

S. Bilalic, M. Veitinger, V. Gruber, M. Zellner, C. Reichel, V. Jordan, G. Böhmig, R. Oehler

 

 

Identification of non-HLA Antigens Targeted By Preformed Allo-Reactive Antibodies in Kidney Transplantation

ThOr04

12.00-12.20

M. Scigelova

 

 

New developments in the ion trapping technology - LTQ Orbitrap Velos

 

12.20-14.00

Lunch

 

 

 

 

Chairman: T. Janáky

 

 

 

ThPl03

14.00-14.40

J. Tőzsér, A. Csutak, É. Csősz, P. Lábiscsák, F. Tóth, P. Boross

 

 

Proteome analysis of human tears from healthy persons and diabetic patients

ThOr05

14.40-15.00

S. Keskin, B. Orhan, E. Buber, O. Celikbicak, B. Salih, M. Ozalp, A. Alp, S. Zeynep, H. Ozen, N. L. Acan

 

 

Therapeutic Effects of Mycobacterial Cell Wall Extracts

ThOr06

15.00-15.20

A. Ingendoh, A. Schneider, S. Lemeer, M. Lubeck, B. Kuester

 

 

Identification of Several Thousand Human Placenta Proteins by CID and ETD on a Novel Ion Trap

 

 

 

 

15.20-17.00

Poster session 2 and coffee break

 

 

 

 

Chairman: K. Bezouska

 

 

 

ThOr07

17.00-17.20

D. Schmid, A. Muck, C. Nagasato, A. Loele, D. Ruder, S. Gebauer-Jung, A. Svatoš, T. Motomura, W. Boland

 

 

Separate the wheat from the chaff – characterizing sex-related proteins from brown algal gametes

ThOr08

17.20-17.40

V. Kertesz, G. J. Van Berkel

 

 

Advanced Mass Spectrometric Approaches for the Analysis of Peptides on Planar Separation Media

ThOr09

17.40-18.00

P. Tompa

 

 

Proteomic identification of intrinsically disordered proteins

 

 

 

 

19.00-23.00

Conference dinner

 

 

Friday, Oct 9, 2009

 

 

 

Chairman: J. Tőzsér

 

 

 

FrPl01

9.00-9.40

M. Karas

 

 

On membrane proteins & membrane protein complexes

FrOr01

9.40-10.00

M. B. Strader, N. Costantino, I. Patel, C. Y. Chen, C. A Elkins, A. J. Makusky, D. E Court, S. P Markey, J. A. Kowalak

 

 

Using an Integrated MS Approach to Elucidate the Biological Function of an Uncharacterized Novel PTM in the Escherichia Ribosomal Protein S12

FrOr02

10.00-10.20

R. Thompson

 

 

The Evolution of Protein Analysis

 

 

 

 

10.20-11.00

Coffee-break

 

 

 

 

Chairman: A. Svatoš

FrPl02

11.00-11.40

J. Peter-Katalinic

 

 

Presence and heterogeneity of carbohydrates on glycoprotein single glycosites: the visible and the invisible

FrOr03

11.40-12.00

O. Ozohanics, L. Drahos, K. Vékey

 

 

Glycosylation, mass spectrometry and informatics

FrOr04

12.00-12.20

B. Scheibe

 

 

Multiplexing in electrophoresis using EttanTM DIGE

 

 

 

 

12.20-14.00

Lunch

 

 

 

Chairman: W. J. Griffiths

FrOr05

14.00-14.20

D. Kavan, H. Mrazek, D. Manglova, P. Basova, V. Kren, K. Bezouska

 

 

Glycomic Analysis of Tumor Cells Reveals The Molecular Determinants Critical for Their Sensitivity for Naturnal Killing and Apoptosis

FrOr06

14.20-14.40

É. Klement, Z. Lipinszki, Z. Kupihár, A. Udvardy, K. F. Medzihradszky

 

 

Enrichment of O-GlcNAc modified proteins by periodate oxidation - hydrazide resin capture approach

FrOr07

14.40-15.00

Alessio Cremonesi, Alexandre Soulard, Suzette Moes, Michael N. Hall, Paul Jenö

 

 

Characterization of the Yeast Rapamycin-sensitive Phosphoproteome

FrOr08

15.00-15.20

Robert van Ling, Evert-Jan Sneekes, Bjorn de Haan, Sebastiaan Eeltink and Remco Swart

 

 

Ultra-high-performance nanoLC-MS/MS analysis of complex proteomic samples

 

15.20-16.00

Coffee break

 

 

 

 

Chairman: L. Drahos

FrPl03

16.00-16.40

M. Marchetti-Deschmann, H. Breiteneder, G. Allmaier

 

 

The peptidome and proteome of snake venoms: challenges and opportunities

FrOr0916.40-17.00Veronika Suni, Garry Corthals
Towards synthetic spectral library of phosphopeptides

FrPl04

17.00-17.40

R. Heeren

 

 

Tissue snapshots: Developments in Imaging Mass Spectrometry

 

 

 

 

17.40-18.00

Closing

 

 

 

Wednesday Posters, Oct 7, 2009

 

 

 

WePo01

J. E. Meza, S. C. Hall, Zs. Nemeth-Toth, S. Bilsborough 

Identification of Differentially Spiked Proteins in Non-Depleted and Non-Fractionated Human Plasma

WePo02

Zs. Nemeth-Toth, N. Tang, S. Bilsborough 

High Throughput Protein Quantitation Using Multiple Reaction Monitoring as a Method for Biomarker Validation

WePo03

E. Jambor, A. Bona, B. Sümegi, L. Mark

Proteomic analysis of intracellular targets for BGP-15

WePo04

M. Laštovičková, M. Synáček, J. Bobáľová

Proteomic study of Barley Grain and Malt

WePo05

E. Hanzlikova, T. Drab,J.  Liberda,

Inhibition studies of sperm-binding in oviduct

WePo06

N.A. Pakharukova, L.K. Pastushkova, O.P. Trifonova, O.A. Valeeva,I. M. Larina

A study of a native variability of serum proteome profile

WePo07

K. Jarkovska, J. Martinkova, H. Skalnikova, R. Hrabakova, P. Halada, D. Kavan, K. Rezabek, S.J. Gadher, H. Kovarova

Ovarian hyperstimulation syndrome biomarker(s) search in human follicular-fluid

WePo08

J. Pospisilova, L. Lorkova, P. Jedelsky, M. Sedinova, J. Zivny, V. Melenovsky, J. Petrak

Proteomic analysis of chronic heart failure in a rat model using iTRAQ chemistry and IEF-LC-MALDI

WePo09

J. Dresler, J. Klimentova, J. Stulik

Studying membrane complexome of F. tularensis using Blue native polyacrylamide gel electrophoresis

WePo10

K. Kotynkova, O. Vanek, P. Pompach, P. Novak, M. Holubova, P. Celadova, K. Bezouska, P. Hanc

Biochemical evidence for specific pairwise interactions of mouse NKR-P1B/D:Clr-b and NKR-P1F:Clr-g receptors engaged in lectin – lectin interactions

WePo11

R. Kob, J. Kelm, F. v Eggeling, A. Baniahmad, C. Melle

Regulation of APC by the COP9 signalosome

WePo12

I. Földi, Á. Hunya, K.A. Kékesi, Z. Szabó, Zs. Darula, E. Hunyadi-Gulyás, T. Janáky, G. Juhász, B. Penke

Altered protein expression profiles from Aβ1-42 treated human SH-SY5Y neuroblastoma cells

WePo13

M. Kłoniecki, A. Jabłonowska, J. Poznański, J. Langridge, Giles K., Tomczyk N, C. Hughes, M. Dadlez

Analysis of Aβ1-40 Peptide Oligomers Using Synapt HDMS System

WePo14

E. Sitkiewicz, M. Dadlez

Impact of the dityrosine cross-links on Aβ peptide oligomerization

WePo15

S. Ren, P. Manaskova-Postlerova, J. Liberda,

Protein and enzymatic characterization of follicular fluid from mature and non-mature follicles

WePo16

J. Martinkova, H. Skalnikova, R. Hrabakova, P. Novak, P. Man, P. Pompach, M. Strohalm, V. Havlicek, P. Dzubak, M. Hajduch, H. Kovarova

Proteome of leukaemic cells after cisplatin treatment – comparison of three independent analytical techniques

WePo17

A. Fučíkova, M. Hubálek, J. Lenčo, J. Stulík, R. Pudil

The SRM Limit of Detection of Proteins Spiked into Undepleted and Depleted

WePo18

I. Chamrad, J. Klaskova, R. Simersky, L. Svehlova, R. Lenobel

Establishment of advanced proteomic techniques for the study of cytokinin-binding protein 1

WePo19

D. Holub, P. Dzubak,G. Rylová, J. Rehulka, M. Hajduch

Optimization of in-gel protein digestion

WePo20

C. Hughes, J. Langridge, N. Nirmalan, R. Banks, Th. McKenna

Investigating Reproducibility of LC-MS Analysis of Complex Peptide Mixtures using FFPE Tissue

WePo21

V. Tambor, J. Lenco, M. Link, R. Pudil, J. Stulik

Cysteinyl Peptide Enrichment Combined with iTRAQ as an Alternative to ICAT

WePo22

Z. Szabó, D. Kovács, J. Szeline Szomor, R. Berkecz, T. Janáky

Comparison of Different Gel-Digestion Protocols by Label-Free Quantification

WePo23

P. Gyulavári, T. Vántus, Gy. Kéri

Development of EGFR and C-met inhibitors

WePo24

P. Rehulka, M. Sebela, J. Chalupova, H. Rehulkova

A preconcentration and purification of enzymatic protein digests with CHCA matrix crystals fixed in a pipette tip for MALDI mass spectrometry analysis

WePo25

P. Man, M. Rey, H. Mrázek, L. Pelosi, P. Pompach, P. Novák, G. Brandolin, E. Forest

Removal of detergents - application to protein mass spectrometry, hydrogen/deuterium exchange and lipid raft proteomics

WePo26

L. Turiák, O. Ozohanics, E. Buzás, K. Vékey

Mass spectrometric analysis of T-cell derived membrane vesicle proteins

WePo27

V. Pós, É. Hunyadi-Gulyás, M. Kabai, R. Caiazzo, I. Jócsák, K. Medzihradszky, N. Lukács

Proteomic analysis of the apoplast of cadmium stressed barley leaf (Hordeum vulgare L.)

WePo28

K.A. Kékesi, E. Hunyadi-Gulyás, Zs. Darula, K.F. Medzihradszky, A. Simor, B. Balogh, A. Czurkó, M. Palkovits, G. Juhász 

Comparative proteomic analysis of the suicide brain

WePo29

E. Szájli, Zs. Birkó, Z. Kele, F. K. Medzihradszky S. Biró

Overlapping Signaling Routes in Streptomyces griseus

WePo30

R.L. Babeluk, L.H. Jakobsen, Kondrup, Jens; E. Roth, S. Baumann, M. Zellner

Impact of high protein diet on platelet proteome in humans

WePo31

J. Šalplachta, D. Flodrová, J. Bobáľová

Investigation of changes of hordein profile during malting process

WePo32

A. Michlmayr, S. Baumann, M. Marchetti-Deschmann, G. Allmaier, T. Bachleitner-Hofmann, C. Burghuber, U. Pluschnig, H. Forstner, M. Bergmann, R. Oehler

The potential of plasma proteomics in predicting response to neoadjuvant chemotherapy in breast cancer patients using 2D-DIGE

WePo33

O.P. Trifonova, L.C. Pastushkova, N.F. Samenkova, N.A. Pakharukova, I.I. Karuzina, A. V. Lisitsa, I. M. Larina

Investigation of extent of variation in plasma proteome

WePo34

M. Zigo, V. Jonakova, P. Manaskova-Postlerova

Isolation and characterization of the sperm surface proteins and their binding studies with zona pellucida glycoproteins

WePo35

A. Prakash, Mingming Ning, T. Rezai, B. Krastins, D. Sarracino, M. Athanas, M. F. Lopez

Development of an SRM-based Apolipoprotein Panel Assay

WePo36

E. Damoc; K. Scheffler; E. Denisov; J. Blethrow; T. Pekar Second; V. Zabrouskov; J. Griep-Raming; A. Makarov; T. Moehring

Overcoming Undersampling in Proteomic Experiments with the Help of a Novel Hybrid Linear Trap-Orbitrap Mass Spectrometer

WePo37

Th. McKenna, C. Hughes, A. Bartlett and J. Langridge

The Use of Multiplexed Discovery Phase Protein Results for the Development of Targeted MRM Assays for Quantification of Proteins.

Thursday Posters, Oct 8, 2009

 

 

 

ThPo01

J. E. Meza, S. C. Hall, Zs. Nemeth-Toth, S. Bilsborough 

Identification of Differentially Spiked Proteins in Non-Depleted and Non-Fractionated Human Plasma

ThPo02

Zs. Nemeth-Toth, N. Tang, S. Bilsborough 

High Throughput Protein Quantitation Using Multiple Reaction Monitoring as a Method for Biomarker Validation

ThPo03

G. Montsko, Cs. Toth, G. Toth, Cs. Farkas, L. Mark

2000-year-old tumour related proteins from a human skeletal remain

ThPo04

E. Csosz, P. Boross, A. Csutak, P. Labiscsak, F. Toth, J. Tozser

Quantitative analysis of proteins in the tear fluid of patients with diabetic retinopathy – an attempt to discover new biomarkers using iTRAQ reagent

ThPo05

M. Šanda, I. Selicharová 

Combination ITRAQ labeling and 2D electrophoresis for quantification of proteomic changes in hepatocytes

ThPo06

A. Váczy, D. Reglődi, L. Márk

LC-MS analysis of pituitary adenylate cyclase activating polypeptide (PACAP) in human body fluids

ThPo07

P. Lábiscsák, P. Boross, É. Csősz, J. Tőzsér

Qualitative proteomic characterization of human tear fluid using LC-MS/MS mass spectrometry

ThPo08

G. Rylová, P. Džubák, D. Holub, M. Špenerová, J. Řehulka, M. Soural, J. Hlaváč, M. Hajdúch

Affinity purification protein targets of anticancer drugs and their identification by technology LC-MSMS

ThPo09

I. Ibragimow, M. Dadlez, J. Debski

Stress induced changes in A. thaliana T87 cells nuclear phosphoproteome.

ThPo10

F. Dycka, M. Lastovickova,M.  Cerny, B. Brzobohaty, J. Bobalova

Phosphopeptides Analysis using Enrichment Techniques and Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry

ThPo11

Gy. Orosz, J. Klem, E. Klement, R. Csáki, K.F. Medzihradszky, K.L. Kovács

Phosphoproteome analysis on the copper regulation of methane monooxigenases in Methylococcus capsulatus (Bath)

ThPo12

Zs. Darula, K.F. Medzihradszky

Mass spectrometric characterization of O-glycopeptides enriched from bovine serum

ThPo13

A.A. Mughal, S. Qureshi

Gene Identification of Chloroplast specific small Heat Shock Proteins in C. album under heat stress

ThPo14

H. Yang, E.Y.M. Fung, A.R. Zubarev,.; R.A. Zubarev, H. Yang

Proteome-scale identification and quantification of isoAsp using on-line electron capture dissociation

ThPo15

H. Y. Tsai, S.T. Chen

Enhance proteomic detection limitation by random nucleotide library

ThPo16

M. Rizwan, I. Miller, F. Tasneem, J. Böhm, E. Razzazi-Fazeli

Analyzing and comparing proteome profile of two strains of Aspergillus ochraceus

ThPo17

M. Svensson, M. Borén, M. Fälth, P. E. Andrén, P. Svenningsson, K. Sköld

Heat Stabization of the tissue proteome for improved proteomics

ThPo18

D. Flodrova, I. Petry-Podgórska, J. Žídková, Z. Szabó, T. Janáky, J. Bobáľová

Application of HPLC and different MS techniques for the study of barley proteins

ThPo19

S. Kędracka-Krok, E. Fic, U. Jankowska, M. Dziedzicka-Wasylewska

Proteomic analysis of proteins changes in the rats hippocampus developing in time after administration of desipramine

ThPo20

M. Bajor, P. Michaluk, L. Kaczmarek

Proteomic discovery of matrix metalloproteinase -9 substrates.

ThPo21

P. Traldi

 

Clinical evaluation of urinary peptides diagnostic for renal failure: a preliminary investigation

ThPo22

J. Mares, Z. Tuma, J. Moravec, A. Krouzecky, T. Karvunidis, M. Matejovic

Characterization of proteins adsorbed to hemodialysis membrane with different anticoagulation agents

ThPo23

D. Ganesh, H. Noedl, G.F. Ecker, P. Chiba 

Proteomics approach to identify the molecular targets by understanding the mechanism of action of novel antimalarials : Strategies Outlined

ThPo24

L. Hernychova, E. Chovancova, J. Damborsky, L. Balonova, I. Pavkova, M. Simsova, M. Capkova, Z. Bilkova, M. Novotny, A. Macela, J. Stulik

Structural and biochemical properties of Francisella tularensis lipoprotein FTT1103

ThPo25

R. Hrabakova, J. Martinkova, H. Skalnikova, P. Novak, L. Radova, P. Dzubak, M. R. Kollareddy, M. Hajduch, S.J. Gadher, H. Kovarova

Multivariate statistical analysis for anti-cancer drug treatment evaluation

ThPo26

P. Halada, K. Kuzelova, D. Grebenova, M. Pluskalova, K. Pavlaskova, J. Suttnar, Z. Hrkal

Impact of Bcr-Abl Inhibition on the Expression of Proteins Involved in Cytoskeleton Structure and Cellular Adhesion to Extracellular Matrix

ThPo27

G. Borbély, I. Szabadkai, Z. Horváth, Z. Varga, T. Vántus, M. Geiszt, Á. Donkó, L. Hunyady, L. Buday, L. Őrfi, Gy. Kéri

Small- molecule inhibitors of NOX4 enzyme..

ThPo28

F. Zivolic, E. Ragazzi, P. Traldi

A MALDI study on curcumin level in organ omogenates as preliminary step for further ion imaging experiments

ThPo29

S. Cristoni, L. Molin, S. Crotti, L. Rossi Bernardi,  R. Seraglia, P. Traldi

Sieve-based device for MALDI sample preparation. II. Instrumental parameterization

ThPo30

L. Wehder, A. Crecelius,U.  Schubert, F. v. Eggeling

Imaging mass spectrometry of head and neck cancer

ThPo31

K. Mazanec, J. Bobalova, K. Slais

Monitoring of proteins in plant materials by the combination of Divergent Flow Isoelectric Focusing and MS

ThPo32

K. Kratochwill, M. Lechner, R.  Herzog, A. Lichtenauer, B. Mayer, A. Rizzi, C. Aufricht

Glutamine mediates cytoprotection in mesothelial cells after exposure to peritoneal dialysis fluid

ThPo33

H. Dong, M. Marchetti-Deschmann, C. Peter Kubicek and G. Allmaier

On-target tryptic digestion of intact Fusarium conidia spores combined with MALDI PSD fragment ion analysis for verification of surface-associated proteins

ThPo34

I. Hegedüs, E. Nagy, J. Takács

Transmission electron microscopic visualization of the structure of cellulase enzyme complex

ThPo35

A. Prakash, Mingming Ning, T. Rezai, B. Krastins, D. Sarracino, M. Athanas, M. F. Lopez

Development of an SRM-based Apolipoprotein Panel Assay

ThPo36

E. Damoc; K. Scheffler; E. Denisov; J. Blethrow; T. Pekar Second; V. Zabrouskov; J. Griep-Raming; A. Makarov; T. Moehring

Overcoming Undersampling in Proteomic Experiments with the Help of a Novel Hybrid Linear Trap-Orbitrap Mass Spectrometer

ThPo37

S. Fuchs, H. Mehlan, H. Kusch, A. Teumer,M. Berth, T. Dandekar, M. Hecker, S. Engelmann, J. Bernhardt

Protecs: A Data Repository for Functional Genomics Studies